SENS is hard, yes, but not too hard to try: a reply to Warner

Abstract

Elsewhere in this issue, Huber Warner writes a critique of my Strategies for Engineered Negligible Senescence (SENS) proposal for the dramatic postponement of age-related functional decline. His commentary advances the debate on SENS to a proper level of measured discourse, something that has been regrettably lacking hitherto, and for this I applaud him. However, his conclusion that SENS is currently so unlikely to succeed that we should not pursue it is, I argue here, incorrect, being based on a range of factual and logical errors.