Caffeine for cognition

Abstract

A systematic review was proposed to evaluate the impact of caffeine consumption on cognitive performance and potential cognitive improvement. Caffeine is a widely consumed psychoactive substance investigated for its stimulant effects and potential neuroprotective properties, specifically regarding dementia and related cognitive disorders. The protocol established a methodological framework to synthesize clinical evidence and provide an objective assessment of the efficacy and safety of caffeine for enhancing cognitive function. Originally formulated and published in 2007 through the Cochrane Dementia and Cognitive Improvement Group, the work aimed to consolidate data from relevant clinical trials. However, the review did not proceed to completion following the development of the initial protocol. Due to a sustained lack of progress in the years following its first assessment, the protocol was formally withdrawn from the Cochrane Library in August 2018. As a result, no updated findings or finalized conclusions regarding the original research question were produced within this specific study framework. – AI-generated abstract.