Chloramphenicol as intervention in heart attacks

Abstract

If the claims of this post are true, this could be an interesting target of EA effort and funding. Assuming the $25 million figure for approval is true, guessing at a $5 million cost for additional overhead for the life of the project, and estimating an average of 20 counterfactual additional QALYs generated per application of the therapy, that’s $30 mm / (400k * 20) = $3.75 per QALY (assuming only applied for one year; cheaper per each year the intervention is used). Valuing a QALY at $50,000, that’s a discount of 99.9925% per QALY and a payback period of approximately 600 patients.